Figure-The results of anti-human CD62p, FITC (clone: AK-4) (solid line) and Mouse IgG1 κ Isotype Control FITC (dotted line) staining in human peripheral blood. Platelet gating was used for analysis.

Overview of SELP Molecular Target Information

Molecular Name: SELP, selectin P

Gene Family: CD molecules; Selectins; Sushi domain containing; C-type lectin domain containing

Alternative name: CD62 PSEL; PADGEM; GMP140; CD62P

Former name: GRMP

Full name: Antigen CD62 granule membrane protein 140kDa; selectin P (granule membrane protein 140kD, antigen CD62); selectin P (granule membrane protein 140kDa, antigen CD62)

A Review of SELP Molecular Targets

CD62P is a 140 kDa transmembrane glycoprotein, also known as P-Selectin. P-Selectin is stored in the α-granules of platelets and Weibel-Palade bodies of endothelial cells and is rapidly translocated to the plasma membrane upon activation. In inflammatory responses, P-Selectin is believed to mediate the initial adhesive interactions between neutrophils and monocytes and the endothelium; during hemostasis, activated platelets interact with neutrophils and monocytes.