Figure-The results of Anti-Human CD79a, PE(Clone: HM47) and Anti-Human CD19, FITC staining on human peripheral blood. The lymphocyte in FSC/SSC was gated for analysis.

Overview of molecular target information of CD79A

Molecular names: CD79A, CD79a molecule

Gene family: CD molecules; V-set domain containing

Alias: MB-1

Former name: IGA

Full name: b-cell antigen receptor complex-associated protein alpha chain; CD79A antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha

Review on Molecular Targets of CD79A

CD79a, also known as mb-1, is a 47kDa membrane glycoprotein, which combines with CD79b to form heterodimeric B cell receptor (BCR). This receptor is responsible for B cell signal transduction, leading to activation, apoptosis or allergy. From the earliest B cells to plasma cells, the expression of CD79a has always existed. CD79 is expressed in B-cell tumors and some non-B-cell malignant tumors, such as AML. Unlike other antibodies that can be expressed in B-cell tumor cells, HM47 is a reliable antibody that recognizes CD79a, so it is a good marker of B cells. Due to the existence of several variants of CD79a, the exact position of epitope may be slightly different.