Fig.-results of anti-human cd19 and mfluor450 (clone: sj25c 1) staining in human peripheral blood. The lymphocyte in FSC/SSC was gated for analysis.

Overview of CD19 molecular target information

Molecular name: CD19, CD19 molecule

Gene family: CD molecules; Immunoglobulin like domain containing; Minor histocompatibility antigens

Full name: CD19 antigen

Review of CD19 molecular targets

CD19 is a 95kDa transmembrane glycoprotein, belonging to the immunoglobulin superfamily, which is expressed in all developmental stages of B cells except plasma cells. CD19 forms a complex with CD21, CD81 and MHC II molecules, and initiates the activation of mature B cells by interacting with B cell receptors. CD19 can promote the proliferation, development and activation of B cells and the maturation of memory B cells. In mice with CD19 deletion, the generation and maturation of B cells in bone marrow and peripheral blood were affected.