Figure-Staining of human peripheral blood The left picture shows Mouse IgG1 Isotype control,APC, and the right picture shows the result of anti-human CD 300e, APC (clone: up-H2). Lymphocytes, granulocytes and monocytes were gated for analysis.

Overview of molecular target information of CD300E

Molecular names: CD300E, CD300e molecule

Alias: IREM2; CLM2

Used name: CD300LE

Full name: CD300 antigen like family member E; CD300e antigen

Review of molecular targets of CD300E

CD300e is a member of cell surface protein glycoprotein family expressed on myeloid cells. CD300e interacts with TYRO protein tyrosine kinase binding protein and is considered as an activation receptor. CD300e is expressed in mature myeloid dendritic cells and monocytes, and down-regulated in immature dendritic cells. In addition, CD300e interacts with DAP-12, which mediates the activation signal. It is reported that the allogeneic reaction of naive T cells is enhanced by activating CD300e.