May-Grunwald-Giemsa Stain is frequently used for staining tissue sections, blood and cell smears, bacteria, chromosomal bands, protozoan parasites, etc. It is especially suitable for staining for Helicobacter Pyloric. Gastric Helicobacter Pyloric (Helicobacter Pyloric), also known as gastric Campylobacter Pyloric (Campylobacter Pyloric), it has been confirmed that this bacterium has a close relationship with chronic gastritis and peptic ulcer, gastric Helicobacter Pyloric is generally curved, S-shaped or seagull-shaped, and sometimes 3 to 4 curved spirals can be seen, often fish-like distribution; the bacterium is most commonly seen in the The bacterium is mostly found in the gastric mucosa between the surface epithelium and the mucosal layer, and close to the surface epithelial cells, part of the epithelial cells into the cytoplasm, the gastric small concavity and the mucous membrane in the superficial gland lumen is also this bacterium.

The staining methods of H. pylori mainly consist of methylene blue method, silver nitrate method, May-Grunwald-Giemsa method (May-Grunwald-Giemsa, MGG method), alkaline magenta method, etc. The silver nitrate method has clear contrast and the stained slides can be preserved for a long time but the operation is more troublesome and time-consuming, while the other methods are easier but the stained slides are prone to discoloration. After Leagene May-Grunwald staining, gastric H. pylori showed blue color, collagen fibers showed red color, erythrocytes showed green color, gastric mucosal epithelium showed light blue color, and the nuclei of the cells showed dark blue color.