Clone number:

Isotype:

Cellular localization: cytoplasm/membrane

Adaptive tissue: paraffin/frozen

Positive Control: Stomach/gastric adenocarcinoma/colon

Antibody incubation time

Antigen repair: heat repair (citric acid)

Claudin-18 is a tight junction protein encoded by the human CLDN18 gene and is a member of the Claudins family.Claudin-18 is specifically expressed in lung and gastric tissues with intact membrane localization on lung and gastric epithelial cells, and electron microscopy shows that it is predominantly localized on the cell-cell boundaries of these cells. These features suggest a potentially important role for Claudin-18 in the structure and function of the tight junctions of lung and stomach.

Claudin-18 antibody reagents can specifically bind to Claudin-18 molecular antigens. Immunohistochemistry kits containing Claudin-18 antibody reagents are suitable for the precise diagnosis of gastric cancer.