Clone number:

Isotype:

Cellular localization: cell membrane

Tissue: paraffin section

Positive Control: Prostate/Skin

Antibody Incubation Time: 1 hour

Antigen repair/heat repair (citric acid)

Type III collagen is not only an essential structural component of many organs, but it is also an important regulator of the diameter of collagen protofibrils of both type I and type II collagen. Type III collagen is also known to play an important role in blood clotting by promoting platelet aggregation through binding to platelets.Type III collagen may also be important in several other human diseases. Increased levels of type III collagen are found in many fibrotic diseases, such as hepatic and renal fibrosis and systemic sclerosis.

Collagen Type III antibody reagents can specifically bind to Collagen Type III molecular antigens. Immunohistochemistry kits containing Collagen Type III antibody reagents are suitable for the precise diagnosis of liver fibrosis and pulmonary fibrosis.