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DOG1 Antibody Reagent
Wholesale Price(RMB):

7321406462847

Product Code:R-0401118Ⅰ-01/R-0401118Ⅰ-02/R-0401118Ⅱ-01/R-0401118Ⅱ-02
Product model: Type Ⅰ (ready-to-use) / Type Ⅱ (manual ready-to-use)
File Number:
Product Introduction

Clone number: OTI1C6


Isotype: rabbit monoclonal antibody


Cellular localization: cell membrane


Tissue: paraffin/frozen


Positive control: Gastrointestinal mesenchymal tumor


Antibody incubation time: 30-60min


Antigen repair: Heat repair (EDTA)


Background Information

The Dog1 gene is located on chromosome 11q13.Preliminary studies have confirmed that Dog1 protein is selectively expressed in gastrointestinal mesenchymal tumors and is a more sensitive and specific marker for GIST compared to KIT/CD117, both for gastrointestinal mesenchymal tumors with mutations in the KIT gene and the PDGFRA gene.


Clinical Value

DOG1 antibody reagents can specifically bind to DOG1 molecular antigens. Immunohistochemistry kits containing DOG1 antibody reagents are suitable for the precise diagnosis of gastrointestinal stromal tumors.