Gastric Helicobacter Pyloric (Helicobacter Pyloric, HP), also known as gastric Campylobacter Pyloric (Campylobacter Pyloric), it has been proved that this bacterium and chronic gastritis and peptic ulcer have a close relationship, gastric Helicobacter Pyloric is generally arc-shaped, S-shaped or seagull-shaped, and sometimes 3 to 4 curved helical, often fish school-like distribution. The bacterium is mostly found in the gastric mucosa between the surface epithelium and the mucosal layer, and close to the surface epithelial cells, part of the epithelial cells into the cytoplasm, the gastric small concavity and the mucous membrane in the superficial gland lumen of the bacterium is also present. Helicobacter pylori staining mainly has borate methylene blue method, silver nitrate method, May-Grunwald-Giemsa method (May-Grunwald-Giemsa, MGG method), alkaline magenta method, etc. The silver nitrate method is clear, the stained film can be stored for a long time, but the operation is more troublesome, time-consuming, the other methods are more simple, but the stained film is prone to discoloration.