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PFG fixative
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Product Code:R-0101014Ⅰ-01/R-0101014Ⅰ-02/R-0101014Ⅰ-03/R-0101014Ⅰ-04/R-0101014Ⅱ-01/R-0101014Ⅱ-02/R-0101014Ⅱ-03
Product Model:Type Ⅰ (ready-to-use) / Type Ⅱ (manual ready-to-use)
Product Usage:Suitable for the fixation of peptide antigens and for immunohistochemical testing of small molecule peptides such as neuropeptides and hormones.
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Product Overview

Principle: Antigenic preservation is achieved through a triple synergistic mechanism: ① p-benzoquinone (1,4-benzoquinone) specifically binds to the free sulfhydryl group (-SH) of peptides; ② formaldehyde rapidly penetrates and forms methylene bridges; and ③ glutaraldehyde cross-links the protein backbone. This combination enhances the antigenicity retention of small molecule peptides to more than 85% (conventional fixative only 40-60%).


Main components: p-benzoquinone, formaldehyde, glutaraldehyde