Clone number:

Homozygous:

Cellular localization: cytoplasm/membrane

Adaptive tissue: paraffin/frozen

Positive control: testis/kidney

Antibody incubation time

Antigen repair: heat repair (citric acid)

Histones play key roles in transcriptional regulation, cell cycle progression, development, and other physiological activities. Histone acetylation/deacetylation alters chromatin structure and influences transcriptional processes.Mutations in the HDAC6 gene correlate with Alzheimer's disease.Overexpression of HDAC6 is associated with tumorigenesis and cell survival while promoting metastasis of cancer cells.

HDAC6 antibody reagents can specifically bind to HDAC6 molecular antigens. Immunohistochemistry kits containing HDAC6 antibody reagents are suitable for the precise diagnosis of multiple myeloma and neurodegenerative diseases (such as Alzheimer's disease).