Clone Number: 304-1A5 & 31A5

Isotype: mouse & rabbit cocktail antibody IgG1 & IgG

Cellular localization: cytoplasm

Tissue: paraffin/frozen

Positive control: mammary gland

Antibody incubation time: 30-60min

Antigen repair: Heat repair (EDTA)

Mammary globulin is a mammary gland associated glycoprotein and is a distant relative of the secretin family, which includes uterine globulin and lipophilin. Unlike other members of the secretin family, the mRNA of mammary globulin is specifically expressed in breast tissue. Studies have shown that this protein is a sensitive reference for studying latent breast cancer cells in sentinel lymph nodes and peripheral blood. In the detection of paraffin tissue sections, the sensitivity of this antibody in detecting mammary globulin in breast cancer tissues is as high as 80%. When used in combination with other mammary specific references such as GCDFP-15, the sensitivity for detecting mammary globulin can reach up to 84%. Detection of mammary globulin plays a crucial role in studying whether primary cancer has metastasized.

The Mammaglobin antibody reagent can specifically bind to the Mammaglobin antigen. The immunohistochemical kit containing the Mammaglobin antibody reagent is suitable for the precise diagnosis of breast cancer.