Clone number: 24B72D11.1

isotype: mouse monoclonal antibody

Cellular localization: nucleus/plasmid/membrane

Tissue: paraffin section

Positive Control:

Antibody incubation time：

Antigen Repair:

MASH1 belongs to the basic helix-loop-helix family and is a key transcription factor for neuroendocrine cell differentiation, contributing to the zonal classification of carcinomas and high-grade neuroendocrine carcinomas.MASH1 is expressed in normal tissues, such as cerebellum, normal thyroid C-cells, and thymic epithelial cells, and in tumor tissues of brain, thymic, and medullary carcinomas such as gliomas, ventricular meningiomas, and medullary carcinomas of the thyroid gland.

MASH1 antibody reagents can specifically bind to MASH1 antigens. Immunohistochemical kits containing MASH1 antibody reagents are suitable for the auxiliary diagnosis of neuroendocrine tumors (such as small cell lung cancer, lung carcinoid) and certain neuroblastocytic tumors.