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MLH1 Antibody Reagent
Wholesale Price(RMB) :

106419006381232

Product Code:R-0401206Ⅰ-01/R-0401206Ⅰ-02/R-0401206Ⅱ-01/R-0401206Ⅱ-02
Product model:Type Ⅰ (ready-to-use) / Type Ⅱ (manual ready-to-use)
File Number:
Product Introduction

Clone number: ES05


Isotype: Mouse monoclonal antibody


Cellular localization: nucleus


Tissue: paraffin/frozen


Positive control: Colorectal cancer


Antibody incubation time: 60min


Antigen repair: Heat repair (EDTA)

Background Information

The DNA Mismatch Repair System consists of enzymes that specifically repair DNA base mismatches to ensure high fidelity of DNA genetic material.The MLH1 gene is located on chromosome 3, and the 87kD protein product it encodes under normal conditions helps to repair errors arising from DNA replication. It is mainly used in tumor research.


Clinical Value

The MLH1 antibody reagent can specifically bind to the MLH1 molecular antigen. The immunohistochemical kit containing the MLH1 antibody reagent is suitable for the precise diagnosis of Lynch syndrome (hereditary non-polyposis colorectal cancer, HNPCC) and sporadic microsatellite instability (MSI-H) tumors.