5701102341660

5701102341660
Clone number: DCS-60.2
isotype: mouse monoclonal antibody
Cellular localization: nucleus
reactivity: paraffin/frozen
Positive control: tonsils
Antibody incubation time: 30-60min
Antigen repair: Heat repair (EDTA)
p21WAF1 is a cell cycle inhibitor. When DNA is damaged, p53 is activated, inducing the expression of the p21WAF1 gene. p21WAF1 binds to the Cyilin-CDK complex, inhibiting CDK activity and leading to the interruption of the cell cycle. It is mainly used in the research of various malignant tumors.
The p21/WAF1 antibody reagent can specifically bind to the p21 molecular antigen. The immunohistochemical kit containing the p21 antibody reagent is suitable for the auxiliary judgment of tumor proliferation inhibition status or chemotherapy sensitivity.