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p21/WAF1 antibody reagent
Wholesale Price(RMB):

5701102341660

Product Code:R-0401237Ⅰ-01/R-0401237Ⅰ-02/R-0401237Ⅱ-01/R-0401237Ⅱ-02
Product model:Type Ⅰ (ready-to-use) / Type Ⅱ (manual ready-to-use)
File Number:
Product Introduction

Clone number: DCS-60.2


isotype: mouse monoclonal antibody


Cellular localization: nucleus


reactivity: paraffin/frozen


Positive control: tonsils


Antibody incubation time: 30-60min


Antigen repair: Heat repair (EDTA)

Background Information

p21WAF1 is a cell cycle inhibitor. When DNA is damaged, p53 is activated, inducing the expression of the p21WAF1 gene. p21WAF1 binds to the Cyilin-CDK complex, inhibiting CDK activity and leading to the interruption of the cell cycle. It is mainly used in the research of various malignant tumors.

Clinical Value

The p21/WAF1 antibody reagent can specifically bind to the p21 molecular antigen. The immunohistochemical kit containing the p21 antibody reagent is suitable for the auxiliary judgment of tumor proliferation inhibition status or chemotherapy sensitivity.