Clone number: polyclonal

isotype: rabbit polyclonal antibody

Cellular localization: nucleus/plasmid/membrane

Tissue: paraffin/frozen

Positive controls: squamous cell carcinoma of skin/tonsils/malignant melanoma/lymph nodes

Antibody incubation time:

Antigen repair: heat repair (citric acid)

S100A4, a member of the S100 family of calcium-binding proteins, is secreted by tumor and stromal cells and promotes tumorigenesis by stimulating angiogenesis.S100A4 plays a role in cell motility, invasion, and microtubule multimerization.Altered chromosomal rearrangements and expression of the S100A4 gene are associated with tumor metastasis.

The S100A4 antibody reagent specifically binds to the S100A4 molecular antigen. The immunohistochemistry kit containing the S100A4 antibody reagent is suitable for assessing tumor metastasis potential (e.g., breast cancer, gastric cancer, colorectal cancer).