Clone number:

Isotype:

Cellular localization: nucleus

Tissue: paraffin/frozen

Positive control: breast/colon cancer

Antibody Incubation Time: 

Antigen repair: heat repair (citric acid)

SOX9 is a transcription factor associated with SRY (sex-determining region of the Y chromosome), which affects sex determination and differentiation, participates in the development of bone, nervous system and pancreas, and is associated with the development of tumors.Mutations or deletions in the SOX9 gene are one of the most important causes of a variety of skeletal diseases in humans and undergoes sex reversal. According to the literature, the expression level of SOX9 in general chondrosarcoma is significantly higher than that in normal cartilage tissues, and it is expressed at a low level in dedifferentiated chondrosarcoma; SOX9 is highly expressed in a variety of tumors, such as prostate, gastric, and hepatocellular cancers, and it is associated with tumorigenesis, development, and prognosis.

The SOX-9 antibody reagent specifically binds to the SOX-9 molecular antigen. The immunohistochemistry kit containing the SOX-9 antibody reagent is suitable for the auxiliary diagnosis of prostate cancer, gastric cancer, liver cancer, and other conditions.