Clone number: A1-1

isotype: mouse monoclonal antibody

Cellular localization: nucleus/plasmid/membrane

Tissue: paraffin section

Positive Control:

Antibody incubation time：

Antigen Repair:

Tau protein is encoded by the single gene for tau, a microtubule-associated protein located on chromosome 17q21.31, and is an axonal microtubule-associated protein. Tau protein is widely distributed within neurons and is also expressed in the ganglia of the myenteric plexus of the gastrointestinal tract and in neuroendocrine cells of the gastrointestinal mucosa. In Alzheimer's disease, increased expression of neurofibrillary tangles is observed. Tau protein expression is also observed in gastrointestinal stromal tumors, gastric neuroendocrine tumors, paragangliomas, intra-abdominal connective tissue proliferative small round cell tumors, and cerebellar neuroblastoma. It is primarily used in research on Alzheimer's disease.

Tau antibody reagents can specifically bind to Tau molecular antigens. Immunohistochemistry kits containing Tau antibody reagents are suitable for the auxiliary diagnosis of Alzheimer's disease.