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TLE1 antibody reagent
Wholesale Price(RMB):

485883319561

Product Code:R-0401316Ⅰ-01/R-0401316Ⅰ-02/R-0401316Ⅱ-01/R-0401316Ⅱ-02
Product model:Type Ⅰ (ready-to-use) / Type Ⅱ (manual ready-to-use)
File Number:
Product Introduction

Clone number: UMAB253


isotype: rabbit monoclonal antibody


Cellular localization: nucleus


Tissue: paraffin/frozen


Positive control: synovial sarcoma


Antibody incubation time: 30-60min


Antigen repair: Heat repair (EDTA)

Background Information

TLE1 is a member of the TLE multigene family and is involved in hematopoiesis, neuronal, and peripheral epithelial differentiation. It is expressed in synovial sarcoma but rarely in neurofibromas and pleomorphic sarcomas. Research data indicate that TLE1 expression in synovial sarcoma has higher sensitivity and specificity than Bcl2, and it is therefore recommended as a marker for synovial sarcoma.


Clinical Value

The TLE1 antibody reagent specifically binds to the TLE1 molecular antigen. The immunohistochemistry kit containing the TLE1 antibody reagent is suitable for the precise diagnosis of synovial sarcoma.