Clone number: 2F3.2

Type: Mouse monoclonal antibody IgG

Cell localization: Cell nucleus/cytoplasm

Suitable tissue: Paraffin/frozen

Positive control: Tonsil

Antibody incubation time: 30-60 min

Antigen retrieval: Heat retrieval (EDTA)

This antigen is a tyrosine protein kinase expressed in T cells and NK cells, and is involved in the activation of T cell receptors. Mutations in this gene cause severe combined immunodeficiency syndrome (SCID) in humans. This antigen is also associated with Ig heavy chain gene mutation status, disease progression, and patient prognosis in patients with chronic lymphocytic leukemia (CLL). Therefore, this antibody can be used in studies of CLL prognosis.

The ZAP-70 antibody reagent specifically binds to the ZAP-70 molecular antigen. The immunohistochemistry kit containing the ZAP-70 antibody reagent is suitable for prognostic stratification of chronic lymphocytic leukemia (CLL).