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ATRX Antibody Reagent
Wholesale Price(RMB):

494959330572

Product Code:R-0401016Ⅰ-01/R-0401016Ⅰ-02/R-0401016Ⅱ-01/R-0401016Ⅱ-02
Product model:Type Ⅰ (ready-to-use) / Type Ⅱ (manual ready-to-use)
file number:
Product Introduction

Clone number: polyclonal


isotype: Rabbit Polyclonal Antibodies


Cellular localization: nucleus


Tissue: paraffin/frozen


Positive control: astrocytes


Antibody incubation time: 30-60min


Antigen repair: Thermal repair (Tri-EDTA)


Background information

Alpha thalassemia / mental retardation syndrome X-linked (ATRX) is a deconjugating enzyme that is absent in diffuse astrocytomas but not in hairy cell astrocytomas, and is useful for differentiating hairy cell and diffuse astrocytomas. Astrocytoma is informative.ATRX in combination with IDH-1 mutation and 1p/19q gene status testing (FISH method) is useful for prognostic assessment of patients with high-grade gliomas.


Clinical Value

ATRX Antibody Reagent binds specifically to the ATRX molecular antigen, and Immunohistochemistry Kits containing ATRX Antibody Reagent are indicated for the precise diagnosis of hairy cell and diffuse astrocytomas.