128223277591485

128223277591485
Clone number:
Isotype:
Cellular localization: cytoplasm/membrane
Adaptive tissue: paraffin/frozen
Positive Control: Stomach/gastric adenocarcinoma/colon
Antibody incubation time:
Antigen repair: heat repair (citric acid)
Claudin-6 is a protein encoded by the human CLDN6 gene and is a member of the Claudins family.Claudin-6 plays a major role in the tight junction-specific closure of cell gaps and is a receptor for hepatitis C virus entry into hepatocytes.Methylation of the Claudin-6 gene may be associated with esophageal tumorigenesis.
Claudin-6 antibody reagents can specifically bind to Claudin-6 molecular antigens. Immunohistochemistry kits containing Claudin-6 antibody reagents are suitable for the auxiliary diagnosis of embryonic tumors (such as testicular germ cell tumors) and certain epithelial cancers (such as gastric cancer and ovarian cancer).