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TP63 (3q28) gene breakage probe reagent
Wholesale Price(RMB):

30006000330066003300660036007200

Product Code:R-0501109Ⅰ-01/R-0501109Ⅰ-02/R-0501109Ⅱ-01/R-0501109Ⅱ-02/R-0501109Ⅲ-01/R-0501109Ⅲ-02/R-0501109Ⅳ-01/R-0501109Ⅳ-02
Probe name:GSP TP63(Centromere)/ GSP TP63(Telomere)
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

Lymphoma

The 2016 edition of the WHO proposed the subtype “ALK-negative ALCL (mesenchymal large cell lymphoma)”, and TP63 rearrangement accounts for about 8% of ALK break-negative cases, with a poor prognosis and a 5-year survival rate of about 17%.TP63 is an oncogene, and gene rearrangements of TP63 are frequently detected in T-cell lymphomas. TP63 is an oncogene, and TP63 rearrangements are frequently detected in T-cell lymphomas, most of which are fusions with TBX1R1, and translocations between TP63 and TBL1 have also been found in follicular lymphomas.