7121187495825

7121187495825
Clone number:
Isotype: see label
Cellular Localization:
Adaptive tissue: paraffin section
Positive Control:
Antibody Incubation Time:
Antigen Repair:
Integrin aM (ITGAM) is a subunit of a protein that forms giant cell antigen (Mac-1) or complement receptor 3 (CR3).ITGAM, also known as CR3A and differentiation antigen cluster molecule 11B (CD11b), is a common myeloid marker with a 50% positive expression rate in acute myeloid leukemias.Co-assay of CD117 and CD11b helps to distinguish acute promyelocytic leukemia (CD11b-positive expression) from cases of acute promyelocytic leukemia (CD11b-negative expression) from cases with restored benign proliferation (CD117-negative expression, CD11b-positive expression).
CD11b Antibody Reagent binds specifically to the CD11b molecular antigen. Immunohistochemistry kits containing CD11b Antibody Reagent are indicated for the precise diagnosis of Acute Myeloid Leukemia (AML), Chronic Myelomonocytic Leukemia (CMML), and Inflammatory/Immune Diseases.