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CDK4 (12q14) Gene Amplification Probe Reagent
Wholesale Price(RMB):

30006000330066003300660036007200

Product Code:R-0501330Ⅰ-01/R-0501330Ⅰ-02/R-0501330Ⅱ-01/R-0501330Ⅱ-02/R-0501330Ⅲ-01/R-0501330Ⅲ-02/R-0501330Ⅳ-01/R-0501330Ⅳ-02
Probe name:GSP CDK4 / CSP 12
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

Amplification of the CDK4 gene adjacent to the MDM2 gene is seen in a variety of tumors. One of the applications: the two markers, MDM2 and CDK4, are expressed in low-grade central osteosarcoma (sometimes confused with fibrous dysplasia) versus parosteal osteosarcoma (not easily differentiated from ossifying myositis and osteochondroma) but not in other similar benign fibrous-osteosarcoma lesions, which contributes to the diagnosis and differential diagnosis of these two types of low-grade osteosarcoma.