简体中文English

FGF19 (11q13) Gene Amplification Probe Reagent
Wholesale Price(RMB):

30006000330066003300660036007200

Product Code:R-0501352Ⅰ-01/R-0501352Ⅰ-02/R-0501352Ⅱ-01/R-0501352Ⅱ-02/R-0501352Ⅲ-01/R-0501352Ⅲ-02/R-0501352Ⅳ-01/R-0501352Ⅳ-02
Probe name:GSP FGF19 / CSP11
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

Approximately 30% of patients with hepatocellular carcinoma are due to abnormalities in the FGF19- FGFR4 signaling pathway. BLU-554 can inhibit FGFR4 with high specificity to treat hepatocellular carcinoma caused by abnormal FGF19-FGFR4 signaling pathway. (BLU-554, a novel targeted agent in clinical trials, targets FGFR4 (paired with FGF19) in patients with advanced hepatocellular carcinoma in the FGF19-amplified or high-expression subtype.)