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PAX3/FOXO1 fusion gene t(2;13) probe reagent
Wholesale Price(RMB):

30006000330066003300660036007200

Product Code:R-0501376Ⅰ-01/R-0501376Ⅰ-02/R-0501376Ⅱ-01/R-0501376Ⅱ-02/R-0501376Ⅲ-01/R-0501376Ⅲ-02/R-0501376Ⅳ-01/R-0501376Ⅳ-02
Probe name:GSP PAX3 / GSP FOXO1
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

Adjuvant diagnosis of adeno-vesicular rhabdomyosarcoma. Specific chromosomal translocations t(2;13)(q35;q14) and t(1;13)(p36;q14) are detected in 70% to 80% of adeno-vesicular rhabdomyosarcomas (ARMS) and the two translocations form the corresponding fusion genes PAX3-FKHR (approximately 75%) and PAX7-FKHR (approximately 25%), respectively; In contrast, these two chromosomal translocations were not seen in embryonal rhabdomyosarcoma.