Figure - Results of human peripheral blood staining for Anti-Human CD11c, PE (Clone:3.9) and Anti-Human CD14, APC. Lymphocytes and monocytes from FSC/SSC were used as gates for analysis.

Overview of molecular target information for ITGAX

Molecular Name: ITGAX, Integrin alpha X Subunit

gene family: CD molecule; integrin alpha subunit; regulator and receptor of the complement system

Synonyms: CD11c

Previously known as: CD11C

Full name: Complement Component 3 Receptor 4 Subunit; Integrin, αX (antigen CD11C (p150), α polypeptide); Integrin, αX (Complement Component 3 Receptor 4 Subunit)

Overview of ITGAX molecular targets

CD11c, known as complement receptor (CR4), is a member of the CD11/CD18 family of adhesion molecules, a type I transmembrane glycoprotein, and is highly expressed on the surface of myeloid DCs.CD11c, as a positive regulator, is involved in the adhesion and migration of DCs, the recognition and presentation of antigens, and the activation of CD4+ and CD8+ T cells, regulating the immune response. cells, regulating the occurrence of immune response and playing an important role in infection and anti-tumor immunity.