Figure - Results of human peripheral blood staining for Anti-Human CD14, FITC (Clone:61D3) and Anti-Human/Mouse CD11b, APC. Monocytes in FSC/SSC were used as a gate for analysis.

Overview of CD14 molecular target information

Molecular name: CD14, CD14 molecule

Gene family: CD molecules; Scavenger receptors

Full name: CD14 antigen

CD14 molecular target overview

CD14 is a glycoprotein expressed on the surface of monocytes, interfollicular macrophages, and a subpopulation of dendritic cells.CD14 CD14 forms a receptor complex with MD-2(LY) and TLR4, which specifically responds and signals to LPS.The CD14/MD-2/TLR4 receptor complex signals through MyD88, TIRAP, and TRAF6, and finally activates NF-κB.