FCGR3B Molecular Target Information

Molecule name: FCGR3B, Fc γ receptor IIIb

Gene family: CD molecule; immunoglobulin-like structural domain containing

Synonyms: CD16; CD16b; FcγRIIIb; FcRIIIb

Formerly known as: FCGR3; FCG3

Full name: IgG Fc fragment, low affinity IIIb, receptor (CD16); IgG Fc fragment, low affinity IIIb, receptor (CD16b); IgG Fc fragment receptor IIIb

Overview of FCGR3B molecular targets

CD16 is a glycosylated phosphatidylinositol-anchored cell membrane protein, a component of the low-affinity Fcγ receptor (FcγRIII). CD16 is a component of the low-affinity Fcγ receptor (FcγRIII) and consists of two isoforms, CD16a and CD16b, with slight structural differences.CD16 is expressed in natural killer cells (only mature natural killer cells, not natural killer precursors or naïve natural killer cells), some T-lymphocytes, neutrophils, and macrophages.CD16 is a glycosylated phosphatidylinositol-anchored chain protein.