FCGR3B Molecular Target Information Overview

Molecular Name: FCGR3B, Fc gamma receptor IIIb

Gene Family: CD molecules; Immunoglobulin like domain containing

Synonyms: CD16; CD16b; FcgammaRIIIb; FcRIIIb

曾用名：FCGR3; FCG3

全称：Fc fragment of IgG, low affinity IIIb, receptor for (CD16); Fc fragment of IgG, low affinity IIIb, receptor (CD16b); Fc fragment of IgG receptor IIIb

FCGR3B Molecular Targets Overview

CD16 is a glycosylated phosphatidylinositol anchor chain of cell membrane proteins, a component of the low affinity Fcγ receptor (FcγRIII). It consists of two isoforms, CD16a and CD16b, with slight structural differences.CD16 is expressed in NK cells (only in mature NK cells, not in NK precursors and naïve NK cells), some T lymphocytes, neutrophils, and macrophages.