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EWSR1/WT1 fusion gene t(11;22) probe reagent
Wholesale Price(RMB):

30006000330066003300660036007200

Product Code:R-0501351Ⅰ-01/R-0501351Ⅰ-02/R-0501351Ⅱ-01/R-0501351Ⅱ-02/R-0501351Ⅲ-01/R-0501351Ⅲ-02/R-0501351Ⅳ-01/R-0501351Ⅳ-02
Probe name:GSP EWSR1 / GSP WT1
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

It is used as an aid in the diagnosis of connective tissue proliferative small round cell tumors;


Pro-connective tissue proliferative small round cell tumors primarily involve children and adolescents, with an age of onset of 10-50 years, a peak age of 30 years, and a male predominance. It is a class of fast-progressing, highly aggressive and highly malignant tumors, occurring mostly in young males. It can involve the peritoneum and has a poor prognosis;


It is mainly differentiated from metastatic small cell carcinoma, malignant mesothelioma, and Ewing sarcoma;


The EWSR1-WT1 fusion gene (t(11;22)(p11;q22)) is a characteristic alteration of (connective tissue-promoting) proliferative small round cell tumors, and the EWS-WT1 fusion gene induces PDGFA expression, leading to the sclerotic features of this tumor.