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PD-L1(9p24)/CSP9 Gene Amplification Probe Reagent
Wholesale Price(RMB):

30006000330066003300660036007200

Product Code:R-0501378Ⅰ-01/R-0501378Ⅰ-02/R-0501378Ⅱ-01/R-0501378Ⅱ-02/R-0501378Ⅲ-01/R-0501378Ⅲ-02/R-0501378Ⅳ-01/R-0501378Ⅳ-02
Probe name:GSP PD-L1 / CSP 9
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

Lung Cancer


PD-L1/2 expression (IHC test) and anti-PD-L1/2 therapy have been written in the NCCNNSCLC 2017V1 edition of the guidelines. While PD-L1/2 expression (upregulation) is enabled by PD-L1/2 gene amplification (9p24.1), the two are positively correlated.


Lymphoma


A recurrent genetic abnormality in nodular sclerosing Hodgkin's lymphoma when the 9p24.1 region is amplified. The PD-L1 and PD-L2 genes encoding PD-1 ligand proteins (also known as CD274 and PDCD1LG2, respectively) in this region are important target genes in the 9p24.1 region.PD-L1(9p24)/CSP9 Gene Amplification Probe Reagents.