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[IGH/CCND1]/[IGH/MAF]/[IGH/MAFB]/[IGH/FGFR3] fusion gene probe reagents
Wholesale Price(RMB):

1200024000132002640013200264001440028800

Product Code:R-0501404Ⅰ-01/R-0501404Ⅰ-02/R-0501404Ⅱ-01/R-0501404Ⅱ-02/R-0501404Ⅲ-01/R-0501404Ⅲ-02/R-0501404Ⅳ-01/R-0501404Ⅳ-02
Probe name:
Product Code:Type I (direct FISH method)/Type II (biotin-labeled indirect FISH method)/Type III (digoxigenin-labeled indirect FISH method)/Type IV (TSA-FISH method)
Registration Number:
Clinical Value

The development of multiple myeloma MM is accompanied by a variety of specific alterations in the number or structure of genes. Gene translocations associated with immunoglobulin heavy chain (IGH) occur in 50% to 60% of MM and are associated with a number of non-random specific translocations, such as t(4; 14) (p16.3; q32) (FGFR3/IGH fusion), t(11; 14) (q13; q32) (CCND1/IGH fusion), t(14; 16) (q32; q23) (MAF/IGH fusion) and t(14; 20) (MAFB/IGH fusion);


These fusion genes can be used for further typing to determine prognosis and therapeutic treatment after a positive initial screening for IGH breaks in multiple myeloma.